The Effect of Ibandronate on Fracture Healing in Rat Tibia Model
نویسندگان
چکیده
Bone is an active and dynamic tissue that builds up the skeleton support of the organism and regenerates itself continuously for a life time [1]. Bone tissue is a very important structure that constitutes the frame in human body in order for the organs to work properly, and the disruption of its integrity is defined as fracture. This pathology formation negatively affects neighboring soft tissues and organ systems [2].
منابع مشابه
Effect of ibandronate on bending strength and toughness of rodent cortical bone
Bone Joint Res 2015;4:99–104. Received 28 March 2014; Accepted after revision 01 April 2015 Objectives There remains conflicting evidence regarding cortical bone strength following bisphosphonate therapy. As part of a study to assess the effects of bisphosphonate treatment on the healing of rat tibial fractures, the mechanical properties and radiological density of the uninjured contralateral t...
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متن کاملEffect of ibandronate on bending strength and toughness of rodent cortical bone: Possible implications for fracture prevention.
OBJECTIVES There remains conflicting evidence regarding cortical bone strength following bisphosphonate therapy. As part of a study to assess the effects of bisphosphonate treatment on the healing of rat tibial fractures, the mechanical properties and radiological density of the uninjured contralateral tibia was assessed. METHODS Skeletally mature aged rats were used. A total of 14 rats recei...
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تاریخ انتشار 2016